{"id":1331,"date":"2024-03-16T10:22:38","date_gmt":"2024-03-16T10:22:38","guid":{"rendered":"http:\/\/marseille-quince.com\/?page_id=1331"},"modified":"2024-03-16T10:32:27","modified_gmt":"2024-03-16T10:32:27","slug":"platform-pipeline","status":"publish","type":"page","link":"https:\/\/marseille-quince.com\/zh\/platform-pipeline\/","title":{"rendered":"\u5e73\u53f0\u53ca\u7ba1\u9053"},"content":{"rendered":"<h3 class=\"wp-block-heading\">\u6211\u5011\u7684\u65b9\u6cd5\uff1a\u91cd\u7de8\u7a0b\u81ea\u566c<\/h3>\n\n\n\n<p> Marseille Quince \u6b63\u5728\u958b\u767c\u4e00\u7a2e\u6709\u91dd\u5c0d\u6027\u7684\u964d\u89e3\u65b0\u65b9\u6cd5\u3002 \u8a31\u591a\u91cd\u8981\u7684\u75be\u75c5\u6a19\u9776\u8d85\u51fa\u4e86\u6cdb\u7d20-\u86cb\u767d\u9176\u9ad4\u9014\u5f91\u7684\u80fd\u529b\u3002 PHLYT\u2122 \u6280\u8853\u5c0d\u81ea\u566c\u4f5c\u7528\u9032\u884c\u91cd\u65b0\u7de8\u7a0b\uff0c\u5728\u9019\u4e9b\u75be\u75c5\u6a19\u9776\u5468\u570d\u7522\u751f\u81ea\u566c\u9ad4\uff0c\u5c0e\u81f4\u964d\u89e3\u3002\u00a0<strong>This is Degradation 2.0.<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/www.casmatx.com\/wp-content\/uploads\/2022\/08\/540_Casma_-2022.06.08_Genevieve-de-Manio-Photography-scaled.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/www.casmatx.com\/wp-content\/uploads\/2022\/09\/134__Casma_-2002.08.10_-_Genevieve-de-Manio-Photography.jpg-scaled.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<p>\u6211\u5011\u7d44\u5efa\u4e86\u4e00\u652f\u4e16\u754c\u4e00\u6d41\u7684\u81ea\u566c\u85e5\u7269\u767c\u73fe\u5718\u968a\uff0c\u5171\u540c\u5de5\u4f5c\u548c\u5b78\u7fd2\u3002 \u900f\u904e\u5229\u7528\u6211\u5011\u5c0d\u81ea\u566c\u548c\u52d5\u529b\u5b78\u7684\u6df1\u523b\u7406\u89e3\uff0c\u6211\u5011\u5efa\u7acb\u4e86 PHLYT\u2122 \u5e73\u53f0\uff0c\u4ee5\u4ee5\u524d\u7121\u6cd5\u60f3\u50cf\u7684\u65b9\u5f0f\u64f4\u5c55\u6a19\u9776\u964d\u89e3\u3002<br><br>\u5167\u90e8\u9a57\u8b49\u5df2\u7d93\u78ba\u5b9a\u4e86\u660e\u78ba\u7684\u81ea\u566c\u9776\u9ede\uff0c\u53ef\u4ee5\u7528\u5316\u5b78\u85e5\u7269\u4f86\u5f62\u6210 PHLYT\u2122 \u7684\u57fa\u790e\u3002 Degradation 2.0 \u662f\u6a21\u7d44\u5316\u7684\uff0c\u56e0\u70ba\u9019\u7a2e\u81ea\u566c\u9776\u5411\u5316\u5b78\u53ef\u7528\u65bc\u958b\u767c\u91dd\u5c0d\u7f55\u898b\u548c\u5e38\u898b\u75be\u75c5\u7684\u7279\u5b9a\u964d\u89e3\u5291\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">PHLYT\u2122\u5e73\u53f0<\/h2>\n\n\n\n<p>\u7570\u96d9\u529f\u80fd\u5316\u5b78\u5df2\u88ab\u958b\u767c\u51fa\u4f86\uff0c\u4ee5\u4fc3\u9032\u81ea\u566c\u8abf\u7bc0\u5291\u5411\u75be\u75c5\u6a19\u9776\u7684\u52df\u96c6\uff0c\u5f9e\u800c\u5c0e\u81f4\u6a19\u9776\u5468\u570d\u7684\u81ea\u566c\u9ad4\u751f\u7269\u767c\u751f\u3002 \u6211\u5011\u5df2\u7d93\u8b49\u660e\uff0c\u9019\u7a2e\u65b9\u6cd5\u80fd\u5920\u4ee5\u5f37\u6709\u529b\u7684\u65b9\u5f0f\u964d\u89e3\u591a\u7a2e\u75be\u75c5\u9776\u9ede\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/www.casmatx.com\/wp-content\/uploads\/2022\/09\/scientific_illustration_still_12.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">PHLYT\u2122 \u7684\u95dc\u9375\u6210\u5206<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>\u81ea\u566c\u77e5\u8b58\u6211\u5011\u7684\u5718\u968a\u64c1\u6709\u9818\u5148\u7684\u81ea\u566c\u884c\u696d\u5c08\u5bb6\u3001\u4e16\u754c\u4e00\u6d41\u7684\u7814\u767c\u80fd\u529b\u4ee5\u53ca\u5ee3\u6cdb\u7684\u81ea\u566c\u548c\u86cb\u767d\u8cea\u7a69\u614b\u5b78\u8853\u5148\u9a45\u7db2\u7d61\u3002<\/li><li>\u76ee\u6a19\u8b58\u5225\u6211\u5011\u5728\u81ea\u566c\u3001\u75be\u75c5\u904e\u7a0b\u548c\u5316\u5b78\u751f\u7269\u5b78\u65b9\u9762\u7684\u6df1\u539a\u5c08\u696d\u77e5\u8b58\u4f7f\u5f97\u6211\u5011\u80fd\u5920\u767c\u73fe\u53ef\u4ee5\u964d\u89e3\u591a\u7a2e\u75be\u75c5\u76ee\u6a19\u7684\u81ea\u566c\u86cb\u767d\u3002<\/li><li>\u914d\u9ad4\u767c\u73fe\u6211\u5011\u7684\u81ea\u566c\u5c0f\u5206\u5b50\u914d\u9ad4\u767c\u73fe\u5f15\u64ce\u80fd\u5920\u958b\u767c PHLYT\u2122 \u964d\u89e3\u5291\u3002 \u6211\u5011\u64c1\u6709\u4f7f Degradation 2.0 \u6210\u70ba\u73fe\u5be6\u7684\u914d\u9ad4\u3002<\/li><li>\u75be\u75c5\u76ee\u6a19\u4e86\u89e3\u5728\u4f55\u8655\u4ee5\u53ca\u5982\u4f55\u90e8\u7f72 PHLYT\u2122 \u6280\u8853\u5c0d\u65bc\u6210\u529f\u7684\u6cbb\u7642\u958b\u767c\u81f3\u95dc\u91cd\u8981\u3002 \u6211\u5011\u4e86\u89e3\u75be\u75c5\u6a19\u9776\u7684\u5206\u5b50\u7279\u5fb5\uff0c\u9019\u4e9b\u7279\u5fb5\u4f7f\u5b83\u5011\u8655\u65bc PHLYT\u2122 \u4ecb\u5c0e\u7684\u964d\u89e3\u7684\u6700\u4f73\u4f4d\u7f6e\u3002<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Videos<\/h2>\n\n\n\n<div class=\"wp-block-columns has-2-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h4 class=\"wp-block-heading\">\u81ea\u566c&nbsp;<\/h4>\n\n\n\n<figure><iframe src=\"https:\/\/player.vimeo.com\/video\/751320085?h=487c11f923&amp;badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479\" allowfullscreen=\"\"><\/iframe><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h4 class=\"wp-block-heading\">PHLYT\u2122&nbsp;<\/h4>\n\n\n\n<figure><iframe src=\"https:\/\/player.vimeo.com\/video\/751320280?h=cb06751a47&amp;badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479\" allowfullscreen=\"\"><\/iframe><\/figure>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"> Marseille Quinc\u00e9 \u5168\u8cc7\u7ba1\u9053<\/h2>\n\n\n\n<p> Marseille Quince \u7684 PHLYT\u2122 \u6280\u8853\u53ef\u4ee5\u964d\u89e3\u8a31\u591a\u8d85\u51fa\u6cdb\u7d20\u86cb\u767d\u9176\u9ad4\u7cfb\u7d71\u80fd\u529b\u7684\u75be\u75c5\u6a19\u9776\u3002 \u6211\u5011\u6b63\u5728\u63a8\u9032\u4e00\u7cfb\u5217\u964d\u89e3\u5291\u7684\u767c\u73fe\uff0c\u9019\u5c07\u6d88\u9664\u591a\u7a2e\u75be\u75c5\u9a45\u52d5\u56e0\u7d20\u3002 \u5176\u4e2d\u4e00\u4e9b\u9805\u76ee\u5c07\u7531\u6211\u5011\u81ea\u5df1\u958b\u767c\uff0c\u53e6\u4e00\u4e9b\u5247\u900f\u904e\u5408\u4f5c\u5925\u4f34\u95dc\u4fc2\u958b\u767c\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"273\" src=\"https:\/\/marseille-quince.com\/wp-content\/uploads\/2024\/03\/program-1024x273.png\" alt=\"\" class=\"wp-image-1334\" srcset=\"https:\/\/marseille-quince.com\/wp-content\/uploads\/2024\/03\/program-1024x273.png 1024w, https:\/\/marseille-quince.com\/wp-content\/uploads\/2024\/03\/program-350x93.png 350w, https:\/\/marseille-quince.com\/wp-content\/uploads\/2024\/03\/program-300x80.png 300w, https:\/\/marseille-quince.com\/wp-content\/uploads\/2024\/03\/program-768x204.png 768w, https:\/\/marseille-quince.com\/wp-content\/uploads\/2024\/03\/program.png 1142w\" sizes=\"(max-width: 767px) 89vw, (max-width: 1000px) 54vw, (max-width: 1071px) 543px, 580px\" \/><\/figure>","protected":false},"excerpt":{"rendered":"<p>Our approach: Reprogramming autophagy Marseille Quinc\u00e9 is developing a new way to do targeted degradation. Many important disease targets go beyond the capacity of the ubiquitin-proteasome pathway. The PHLYT\u2122 technology reprograms autophagy to generate autophagosomes around these disease targets resulting in degradation.\u00a0This is Degradation 2.0. We have amassed a world-class autophagy drug discovery team that &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/marseille-quince.com\/zh\/platform-pipeline\/\" class=\"more-link\">\u7e7c\u7e8c\u95b1\u8b80<span class=\"screen-reader-text\"> &#8220;Platform &#038; pipeline&#8221;<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"footnotes":""},"class_list":["post-1331","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/marseille-quince.com\/zh\/wp-json\/wp\/v2\/pages\/1331","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/marseille-quince.com\/zh\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/marseille-quince.com\/zh\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/marseille-quince.com\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/marseille-quince.com\/zh\/wp-json\/wp\/v2\/comments?post=1331"}],"version-history":[{"count":3,"href":"https:\/\/marseille-quince.com\/zh\/wp-json\/wp\/v2\/pages\/1331\/revisions"}],"predecessor-version":[{"id":1336,"href":"https:\/\/marseille-quince.com\/zh\/wp-json\/wp\/v2\/pages\/1331\/revisions\/1336"}],"wp:attachment":[{"href":"https:\/\/marseille-quince.com\/zh\/wp-json\/wp\/v2\/media?parent=1331"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}