Scientific studies have demonstrated that AKG inhibits ATP synthase, thereby reducing mTOR pathway activation, while simultaneously activating AMPK to help regulate cellular metabolism, thus achieving anti-aging effects. Marseille-Quince’s AKG PRO boasts superior quality compared to conventional products, with a purity of up to 98%, a Ca-AKG content of 200mg/capsule, and a PQQ content of 10mg/capsule, meeting the body’s daily needs.
適合
weight management, metabolic disorders, muscle development, lack of energy, memory decline, and work stress.
Alpha-ketoglutarate (AKG) is a key molecule in the Krebs cycle (cellular energy production). In addition to its metabolic functions, AKG has attracted attention for its potential anti-aging benefits, including promoting cell repair, reducing oxidative stress, and regulating aging-related pathways. This article explores the multifaceted effects of AKG, focusing on its anti-aging effects.
1. Energy production and metabolism
AKG plays a crucial role in the conversion of nutrients into ATP (the body’s energy unit). It supports mitochondrial function, which declines with age. By optimizing energy metabolism, AKG can slow age-related fatigue and muscle loss.
2. Antioxidant properties
AKG can neutralize free radicals and increase the production of glutathione (a key antioxidant), thereby reducing oxidative stress—a major contributing factor to aging and diseases such as Alzheimer’s.
3. Collagen Synthesis and Tissue Health
AKG is a cofactor for collagen synthesis, helping to maintain skin elasticity, joint health, and wound healing. Collagen decreases with age, leading to wrinkles and arthritis; AKG may help alleviate these problems.
4. Cell Repair and Longevity
AKG activates autophagy (the process of clearing damaged cellular components) and inhibits the aging-related mTOR pathway. Animal studies have shown that AKG supplementation can extend the lifespan of worms and mice by up to 50%.
5. Epigenetic Regulation
AKG affects DNA methylation (an epigenetic mechanism that regulates gene expression) and may slow cellular decline by modulating aging-related genes.
6. Clinical Studies and Safety
Human trials are limited, but early studies suggest that AKG may improve metabolic health in older adults. The common dosage is 500–2000 mg/day; mild gastrointestinal upset is a rare side effect. Consult a healthcare professional before use.
AKG, as a multi-target anti-aging compound, connects energy metabolism and cellular lifespan. Although research is still ongoing, its potential to extend healthy lifespan makes it a key area for future research!
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